詳細說明
Catalogue Number : 9876741
Description
(+)-BAY-K-8644 is a L-type calcium channel agonist with negative vasodilatory and inotropic effects. The (+)-BAY-K-8644 enantiomer exhibits opposite biological effects to the racemate and (-)-BAY-K-8644 molecules.
Additional Information
Applications | FA |
Synonyms: | (R)-(+)-BAY K 8644; CHEMBL105672; (R)-(+)-Bay K8644; methyl (4R)-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate |
Formulation: | Crystalline solid |
Chemical Name: | methyl (4R)-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate |
Molecular Formula: | C16H15F3N2O4 |
Molecular Weight: | <div "class="productview-attribute-conten_div">356.3 |
CAS Number | 98791-67-4 |
Purity: | 鈮?8% |
Storage Conditions: | Product should be kept at-20°C. |
References: | Garcia, A. G., Sala, F., Reig, J. A., Viniegra, S., Frias, J., Fonteriz, R., & Gandia, L. (1984). Dihydropyridine BAY-K-8644 activates chromaffin cell calcium channels. Franckowiak, G., Bechem, M., Schramm, M., & Thomas, G. (1985). The optical isomers of the 1, 4-dihydropyridine BAY K 8644 show opposite effects on Ca channels. European journal of pharmacology, 114(2), 223-226. Yamamoto, H., Hwang, O. K., & Van Breeman, C. (1984). Bay K8644 differentiates between potential and receptor operated Ca 2+ channels.European journal of pharmacology, 102(3), 555-557. |
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