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Milliplex Catalog ID.HCCBP3MAG-58K-03.MAG Circulating Cancer Panel 3

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Milliplex Catalog ID.HCCBP3MAG-58K-03.MAG Circulating Cancer Panel 3信息二維碼

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Total-I?B? Magnetic Bead MAPmate Phospho IkB? Magnetic Bead MapMate Phospho-I?B? (Ser32) Mag Bead MAPmate Total CREB Magnetic Bead MAPmates Phospho CREB Magnetic Bead MAPmate Phospho-CREB (Ser133) Mag Bead MAPmate

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    基本參數(shù)

    詳細(xì)說明

    Replacement Information

    重要規(guī)格表

    Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
    Catalase, Cathepsin D, Galectin-3, Ferritin, Fibroblast Activation Protein, IGFBP-3, Melanoma Inhibitory Activation Protein, Myeloperoxidase, Sex Hormone Binding GlobulinHMplexLuminex xMAP
    Description
    Catalogue NumberHCCBP3MAG-58K
    Trade Name

    • MILLIPLEX

    DescriptionMILLIPLEX MAP Human Circulating Cancer Biomarker Magnetic Bead Panel 3 - Cancer Multiplex Assay
    OverviewMILLIPLEX MAP Circulating Cancer Biomarker Magnetic Bead Panel 3 consists of 9 circulating cancer biomarkers that can be used to study a wide range of tumor types.
    Background InformationCancer research has always focused on intracellular biomarkers, such as HER2 and B-Raf, and in recent years, more and more attention has shifted to include extracellular cancer biomarkers. While the use of intracellular markers in research helps clarify the process of oncogenesis, circulating cancer biomarkers give insight into how the body responds to the presence of a tumor, the dysregulation of homeostasis and the relationship between a tumor and its environment. Study of isolated biomarkers, whether intracellular or circulating, is often inadequate to fully characterize the complex relationship between tumor and non-tumor. Consequently, multianalyte panels have become essential tools that enable researchers to measure cancer biomarkers simultaneously, teasing out these relationships and applying them to understand tumor biology.
    References
    Product Information
    Detection methodLuminex xMAP
    ConfigurationDesign your multiplex kit by choosing available analytes within this panel.
    Precision, %

    • Intra Assay: 5 - 8

    • Inter Assay: 5 - 17

    Panel TypeMAGNETIC Circulating Cancer
    Applications
    Applicationirculating Cancer Biomarker Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple oncology biomarkers in various tumor types in human serum, plasma and cell culture samples.
    Key Applications

    • Multiplexing

    Application Notes? This is an overnight incubation assay requiring 25 μL of 1:50 dilution plasma or serum, or 25 μL of diluted tissue/cell lysate or culture supernatant per well (dilution factors may vary).
    ? This kit may be used for the analysis of all or any combination of the cancer biomarkers in serum, plasma or tissue/cell lysate and culture.
    Biological Information
    Species Reactivity

    • Human

    Analytes Available

    • Catalase

    • Cathepsin D

    • Galectin-3

    • Ferritin

    • Fibroblast Activation Protein

    • IGFBP-3

    • Melanoma Inhibitory Activation Protein

    • Myeloperoxidase

    • Sex Hormone Binding Globulin

    Assay PanelEverything you need in a single kit.
    Cross ReactivityCross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
    Accuracy

    • 74% - 126%

    Physicochemical Information
    Sensitivity

    • Refer to kit protocol for sensitivities of individual biomarkers.

    Standard Curve Range

    • 0.07 - 50 ng/mL: Catalase, Fibroblast Activation Protein α

    • 0.27 - 200 ng/mL: Cathepsin D, IGFBP3

    • 0.03 - 25 ng/mL: Ferritin

    • 0.004 - 3 ng/mL: Galectin-3

    • 0.1 - 75 ng/mL: Melanoma Inhibitory Activity Protein

    • 0.02 - 20 ng/mL: Myeloperoxidase

    • 0.03 - 25 nM: Sex Hormone Binding Globulin*

      *SHBG Standard was calibrated against WHO standard 08/266 and 250 ng/mL standard was equivalent to 25 nM of WHO standard

    Dimensions
    Materials Information
    Toxicological Information
    Safety Information according to GHS
    Safety Information
    Product Usage Statements
    Usage Statement

    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

    Storage and Shipping Information
    Storage ConditionsRecommended storage for kit components is 2 - 8°C.
    Packaging Information
    Material Size96-well plate
    Transport Information
    Supplemental Information
    Specifications
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