• Species Reactivity

  Human

• Specificity

  Stains human GPR15-transfected cells but not irrelevant transfectants.

• Source

  Monoclonal Mouse IgG2b Clone # 367902

• Immunogen

  NS0 mouse myeloma cell line transfected with human GPR15    
  Met1-Leu360    
  Accession # P49685

• Formulation

  Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

• Label

  Alexa Fluor 405

Applications

• Recommended    
  Concentration

  Sample

• Flow Cytometry

  0.25-1 μg/10    ⁶ cells

  Human whole blood CD4    ⁺ lymphocytes and HEK293 human embryonic kidney cell line transfected with human GRP15 and eGFP

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Preparation and Storage

• Shipping

  The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

• Stability & Storage

  Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: GPR15

GPR15, also known as BOB, is a seven-transmembrane G protein-coupled receptor that is expressed in CD4  ⁺ T cells and alveolar macrophages. GPR15 functions as a cellular co-receptor for some isolates of HIV-1, HIV-2, and SIV through interactions with several viral envelope proteins. Human GPR15 shares 96%?100% amino acid sequence identity with chimpanzee, macaque, and rhesus GPR15, and 76% with mouse GPR15.

• Long Name:

  G Protein-coupled Receptor 15

• Entrez Gene IDs:

  2838 (Human); 71223 (Mouse)

• Alternate Names:

  Bob; Brother of Bonzo; G protein-coupled receptor 15; GPR15; G-protein coupled receptor 15; MGC126828; MGC126830