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2-溴-4-碘-5-甲基吡啶信息二維碼

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￥200.00元/mg
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CAS 1227577-26-5
級別 國標/gb
品牌 macklin
規(guī)格 5g
含量 98.0%
管控 2-8°C, 避光, 惰性氣體
庫存碼 B756679-100mg
分子式 C6H5BrIN
分子量 297.92
英文名 2-Bromo-4-iodo-5-methylpyridine
數(shù)量
+-
庫存1mg ? 起訂1mg
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信息二維碼

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中文名:恩曲他濱;恩曲他濱
中文別名:恩曲他濱;5-氟-1-(2R,5S)-[2-羥甲基-1,3-氧硫環(huán)-5-酰]胞嘧啶;依曲西他濱;鹽酸恩曲他濱;恩曲他濱 EMTRIVA;恩曲他濱
英文名稱：Emtricitabine(Emtriva)
英文別名：EMTRICITABINE;Emtriva;Coviracil;BW1592;BW-1592;BW 1592;Atripla;
CAS No.:143491-57-0
分子式:C8H10FN3O3S
分子量:247.25
性狀:

屬性

存貯條件儲存溫度-20°C

描述

產品介紹Emtricitabine 是一種核苷逆轉錄酶抑制劑，IC50為27.7 μM用途A HIV-1 reverse transcriptase (HIV-1 RT) inhibitor生化機理Emtricitabine is a nucleoside analogue which inhibits the reverse nucleoside transcriptase enzyme. Structurally this antiviral agent is similar to Lamivudine. This agent is effective at targeting HIV and HBV viruses since these viruses replicate in a reverse transcriptase manner. Studies indicate that the structure of Emtricitabine, specifically the unnatural β-L structural configuration produce greater antiviral effects in vitro on HIV and HBV than other antiviral agents. To activate Emtricitabine it needs to undergo multistep intracellular phosphorylation by various cellular kinases. These studies suggest that Emtricitabine competitively inhibits HIV-1 reverse transcriptase (HIV-1 RT) and can cause termination of DNA chain elongation in the virus via incorporation into the viral genome.包裝E125328-25mg,E125328-250mg in glass bottle
儲存:儲存溫度-20°C
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用途:

Emtricitabine(Emtriva) is a nucleoside reverse transcriptase inhibitor with an IC50 of 27.7 μM. [1] The drug works by inhibiting reverse transcriptase, the enzyme that copies HIV RNA into new viral DNA. By interfering with this process, which is central to the replication of HIV, emtricitabine can help to lower the amount of HIV, or "viral load", in a patient’s body and can indirectly increase the number of immune system cells (called T cells or CD4+ T-cells). Both of these changes are associated with healthier immune systems and decreased likelihood of serious illness. [2]
[1] Tang YB et al. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6350-3.

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