酚嘧啶 撲蟯靈

生物活性靶點體內(nèi)研究 用途與合成方法 MSDS 酚嘧啶 撲蟯靈價格(試劑級) 上下游產(chǎn)品信息

中文名稱	酚嘧啶 撲蟯靈
中文同義詞	含 4,4′-亞甲基雙(3-羥基-2-萘甲酸) 的 1-甲基-2-(3-羥基苯乙烯基)-1,4,5,6-四氫嘧啶化合物;酚嘧啶 撲蟯靈;酚嘧啶;奧克太;牛津猩猩;(E)-3-(2-(1-甲基-1,4,5,6-四氫嘧啶-2-基)乙烯基)苯酚 4,4'-亞甲基雙(3-羥基-2-萘甲酸) (1:1)
英文名稱	OXANTEL PAMOATE
英文同義詞	2-Naphthalenecarboxylic acid, 4,4-methylenebis3-hydroxy-, compd. with 3-(1E)-2-(1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)ethenylphenol (1:1);1-methyl-2-(3-hydroxyphenylethenyl)-1,4,5,6-tetrahydropyrimidine compound with 4,4'-methylenebis(3-hydroxy-2-naphthoic acid);4,4'-Methylenebis(3-hydroxy-2-naphthoic) acid, compound with (E)-3-(2-(1,4,5,6-tetrahydro-1-methylpyrimidin-2-yl)vinyl)phenol (1:1);Einecs 272-332-6;Phenol, 3-(2-(1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)ethenyl), (E)-, 4,4'-methylenebis(3-hydroxy-2-naphthalenecarboxylate) (1:1) (salt);1-METHYL-2-[3-HYDROXYPHENYLETHENYL]-1,4,5,6-TETRAHYDROPYRIMIDINE COMPOUND WITH 4,4'-METHYLENEBIS[3-HYDROXY-2-NAPHTHOIC ACID];OXANTEL PAMOATE;4,4'-methylenebis[3-hydroxy-2-naphthoic] acid, compound with (E)-3-[2-(1,4,5,6-tetrahydro-1-methylpyrimidin-2-yl)vinyl]phenol (1:1)
CAS號	68813-55-8
分子式	C49H48N4O8
分子量	820.93
EINECS號	272-332-6
相關(guān)類別	小分子抑制劑;醫(yī)藥原料;有機中間體;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;MOTILIUM
Mol文件	68813-55-8.mol
結(jié)構(gòu)式

酚嘧啶 撲蟯靈 性質(zhì)

酚嘧啶 撲蟯靈 用途與合成方法

生物活性

Oxantel pamoate 是一種廣泛使用的驅(qū)蟲劑，有效針對Trichuris muris 和鉤蟲。

靶點

Antiparasitic

體內(nèi)研究

The activity of the veterinary drug Oxantel pamoate is studied against     Trichuris muris    ,     Ancylostoma ceylanicum    and     Necator americanus    . An ED     ₅₀    s of 4.7 mg/kg is calculated for Oxantel pamoate against     T. muris    in mice. Combinations of Oxantel pamoate with pyrantel pamoate behaved antagonistically (combination index (CI)=2.53). Oxantel pamoate combined with Levamisole, Albendazole or Ivermectin using ratios based on their ED     ₅₀    s reveals antagonistic effects (CI=1.27, 1.90 and 1.27, respectively). A highly synergistic effect (CI=0.15) is observed when Oxantel pamoate-mebendazole is administered to     T. muris    -infected mice. Oxantel pamoate (10 mg/kg) lacks activity against     Ancylostoma ceylanicum    and     Necator americanus    .

安全信息

MSDS信息

酚嘧啶 撲蟯靈 價格(試劑級)

酚嘧啶 撲蟯靈 上下游產(chǎn)品信息