依來多辛

用途靶點體外研究體內(nèi)研究 用途與合成方法 MSDS 依來多辛價格(試劑級) 上下游產(chǎn)品信息

中文名稱	依來多辛
中文同義詞	依來多辛;麝香蛸素;醋酸依來多辛 ELEDOISINACETATE;醋酸依來多辛 69-25-0;醋酸依來多辛;ELEDOISIN ACETATE 醋酸依來多辛;章魚唾腺精, >99%;章魚唾腺精
英文名稱	Eledoisin
英文同義詞	eledonepeptide;ELEDOISIN;GLP-PRO-SER-LYS-ASP-ALA-PHE-ILE-GLY-LEU-MET-NH2;5-oxo-l-prolyl-l-prolyl-l-seryl-l-lysyl-l-aspartyl-l-alanyl-l-phenylalanyl-l-isoleucylglycyl-l-leucyl-l-methioninamide;PYR-PRO-SER-LYS-ASP-ALA-PHE-ILE-GLY-LEU-MET-NH2;PYR-PSKDAFIGLM-NH2;PGLU-PRO-SER-LYS-ASP-ALA-PHE-ILE-GLY-LEU-MET-NH2;ELEDOSIN
CAS號	69-25-0
分子式	C54H85N13O15S
分子量	1188.4
EINECS號	251-228-4
相關(guān)類別	多肽;醫(yī)藥原料藥;醫(yī)藥原料;proteins;Peptide
Mol文件	69-25-0.mol
結(jié)構(gòu)式

依來多辛 性質(zhì)

依來多辛 用途與合成方法

用途

依來多辛是 NK2 和 NK3 受體的特異性激動劑。

靶點

NK2 and NK3 receptors.

體外研究

Eledoisin (Eledone peptide) increases the value recorded under basal conditions by 24.5±3.7%; this stimulation is significantly (P<0.01) lowered to 13.1±1.9% by the simultaneous presence of CP99994. The same protocol is also used to characterize the sensitivity of Eledoisin stimulation to 0.1 μM SR48968 or 0.1 μM SB222200. SR48968 significantly (P < 0.01) lower the stimulation by Eledoisin, while SB222200 has no effect. Eledoisin stimulation is reduced by CP99994 and SR48968, NK1 and NK2 antagonists, respectively.

體內(nèi)研究

Eledoisin (Eledone peptide; 0.1-1 nmol/kg) injected into rats produces a biphasic cardiovascular response that consists of an initial fall of systemic blood pressure (8-15 mm Hg) followed by a rise (20-22 mm Hg). Intracerebroventricular injection of Eledoisin produces an enhancement of grooming and scratching behavior in mice.

安全信息

MSDS信息

依來多辛 價格(試劑級)

依來多辛 上下游產(chǎn)品信息